Pyrrole's Disorder

Pyrrole’s disorder (PD) is a chemical imbalance affecting mood, energy and behaviour that I’m seeing very often among both adults and children. PD is a genetic disorder, so if one family member has it, it is quite likely that there are others in the family who also have it.

In PD, during the process of producing haemoglobin, there is excessive production of the metabolite hydroxyhemopyrrolin-2-one (HPL) (Pyrrole for short). Not only are these metabolites neurotoxic, but they bind zinc, B6, GLA and biotin, depleting the body of of key nutrients required for energy production, detoxification and synthesis of serotonin and hormones. As B6, Zinc and biotin are also needed for heme production, this results in reduced ability of haemoglobin to deliver oxygen to cells.

Many of the symptoms of Pyrrole’s revolve around the disorder’s impact on production of brain chemicals, or neurotransmitters. Low zinc and B6 can deplete our calming neurotransmitters such as serotonin and GABA. It can cause imbalances in stimulating brain chemicals such as dopamine, and also affect melatonin levels. These changes can lead to all sorts of mood and nervous system symptoms, including behavioural and sleep problems. Any process that depends on zinc and/or B6 can be affected by the condition.

Common signs of PD include:
- anxiety and/or depression
- aggressive outbursts
- restlessness
- difficulty with sleep
- tantrums
- inability to deal with stress
- disruptive behaviour

Among children, I’m seeing a lot of young boys affected by problems with emotional regulation being categorised as borderline ADHD. Quite often, I find that these boys respond well to nutritional correction, especially so if there is a family history of Pyrrole’s disorder (PD).

Among adults, I’m seeing many women with anxiety, inability to cope with stress and fatigue who have this chemical imbalance.

If you suspect that Pyrrole’s could be an issue in your family, you can do a non-invasive urine test to find out. Contact cyena@highervibration.com.au to discuss.

Photo by Sharon McCutcheon on Unsplash